NACSELD is a consortium of tertiary-care hepatology centers in North America. NACSELD was initially formed to study the role of infections in adult hospitalized patients with cirrhosis in 2011 from whom information was collected prospectively regarding admission data and significant events during hospital stay. In 2013, data collection was expanded its role to include all hospitalized patients with cirrhosis (infected and non-infected). NACSELD currently consists of 16 centers across USA and Canada. The database contains information on 3,000 hospitalized patients with cirrhosis. NACSELD investigators have published several studies and presented leading abstracts in international conferences pertaining to the inpatient course of cirrhosis, and the subsequent outcomes of patients after discharge.
The Steering Committee of NACSELD consists of Jasmohan Bajaj, K Rajender Reddy, Jacqueline O’Leary, Guadalupe Garcia-Tsao, Florence Wong and Patrick Kamath. The lead biostatistician is Leroy Thacker, based at Virginia Commonwealth University, where the REDCAP database is also based. The collection of data and analysis for the infection-only study was unfunded but the current study is sponsored by an investigator-initiated grant from Grifols Pharmaceuticals.